Treatment of dry mouth symptoms (iatrogenic hyposialia or asialia of medicinal or radiotherapy origin). OGT-based solution for endo-buccal sprays. Controlled clinical trials demonstrate that the solution rapidly and significantly improves the symptoms associated with dry mouth.

Triple effect of the solution:

• lubricant
• adhesive, with the formation of a lipid film whose role is to limit insensible water loss and restore the viscoelasticity of the oral mucosa
• Protective against local aggressions

PUBLICATIONS

ARTICLE 1

‘’Efficacy of a new oral lubricant solution in the management of Psychotropic drug-induced Xerostomia’’

Authors

Stéphane Mouly, MD, PhD, Jean-Baptiste Orler, MD, Yves Tillet PharmD, Anne-Claude Coudert, PharmD, Frantz Oberli, PhD, Philip Preshaw, MD, Jean-François Bergmann, MD

Journal

Journal of Clinical Psychopharmacology: Volume 27. No. 5. October 2007

ARTICLE 2

‘’Xerostomia in the elderly: value of a local treatment by application of an oxidized glycerol triester oral spray compared to a reference artificial saliva’’

Author

Michel Salom

Journal

La Revue de Gériatrie, Tome 31 No. 10 – Dec. 2006 _

ARTICLE 3

‘’Management of xerostomia in older patients: A randomised controlled trial Evaluating the efficacy of a new oral lubricant solution’’

Authors

Stéphane Mouly, Michel Salom, Yves Tillet, Anne-Claude Coudert, Frantz Oberli, Philip M. Preshaw, Stéphane Desjonquères, Jean-François Bergmann

Journal

Drugs & Aging 2007; 24(11); 957-965